Substances
The Uses and Side Effects of the G037 White Oval Pill
Medically Reviewed By
Written By
Last medically reviewed February 17, 2025
Substances
Medically Reviewed By
Written By
Last medically reviewed February 17, 2025
The G037 white oval pill serves as a common prescription medication for managing moderate to severe pain. Medical professionals carefully evaluate each person’s condition before recommending this opioid-based treatment option. The medication works through specific pathways in the central nervous system to reduce pain signals, though it carries significant risks that require close monitoring. Proper usage and awareness of warning signs help ensure safe treatment outcomes for anyone taking this medication.
The G037 white oval pill contains hydrocodone and acetaminophen, making it a combination pain medication that doctors prescribe for moderate to severe pain management.[1] Sold under the brand name Lortab, the white, oval-shaped tablet features the imprint “G037” on one side, helping patients and healthcare workers identify it correctly. This medication belongs to the opioid analgesic class of drugs, which requires careful monitoring and proper prescription documentation.
The hydrocodone component acts as an opioid pain reliever, targeting specific opioid receptors in the brain to alter pain perception and emotional responses to pain.[2] Meanwhile, acetaminophen enhances the pain-relieving effects while helping reduce fever.[3] Physicians typically prescribe this medication for short-term pain management, though some patients might receive it for chronic pain conditions under strict medical supervision.
Doctors determine appropriate dosing based on several factors, including pain severity, medical history, and previous opioid exposure. The standard prescription usually directs patients to take one tablet every four to six hours as needed for pain, with a strict maximum daily limit to prevent acetaminophen overdose. The medication requires secure storage in a locked container, away from others, particularly children, due to its potential for misuse and accidental ingestion.
The G037 white oval pill combines two primary active ingredients: 10 milligrams of hydrocodone bitartrate and 325 milligrams of acetaminophen in each tablet.[4] These ingredients work together to create a potent pain-relieving medication. Hydrocodone functions as the opioid component, while acetaminophen serves as a non-opioid pain reliever and fever reducer.
The medication also contains several inactive ingredients that help form the tablet structure and enhance its stability. These inactive components include microcrystalline cellulose, a binding agent, and silicon dioxide, which prevents the ingredients from clumping together. Additional ingredients include croscarmellose sodium for proper tablet disintegration and magnesium stearate, which helps make the drug.
The specific 10/325-milligram formulation reflects a careful balance that doctors and pharmaceutical companies have determined provides effective pain relief while minimizing the risk of acetaminophen-related liver damage. The Food and Drug Administration has mandated that all prescription acetaminophen combinations must not exceed 325 milligrams per tablet to enhance patient safety.[5]
Many people experience side effects while taking Lortab, a brand-name combination of hydrocodone and acetaminophen. The severity and frequency of side effects can vary based on factors like dosage, individual sensitivity, and duration of use. Healthcare teams monitor these effects closely and may adjust treatment plans accordingly – always follow medical advice when it comes to prescription medication.
Common side effects include:[6]
Lortab can cause severe overdose reactions that require immediate emergency medical attention.[7] Both active ingredients can lead to life-threatening complications when taken in excessive amounts. The risk of overdose increases significantly when people take more than prescribed, combine it with other medications or substances, or take doses too close together.
Signs of hydrocodone overdose appear as severe central nervous system and respiratory depression.[8] The person may display extremely slow or shallow breathing, cold and clammy skin, pinpoint pupils, severe drowsiness or inability to wake up, and bluish lips or fingernails. Without prompt medical intervention, these symptoms can progress to respiratory failure, coma, or death.
Acetaminophen overdose presents different risks. While symptoms might not appear immediately, excessive acetaminophen can cause severe liver damage within 24 to 48 hours.[9] Early signs include nausea, vomiting, and abdominal pain. Later stages may involve yellowing of the skin and eyes, confusion, and bleeding problems. Acetaminophen overdose requires immediate hospital treatment to prevent liver failure.
Proper identification of medications plays a crucial role in preventing dangerous errors and ensuring safe treatment outcomes. Taking the wrong medication or incorrect dosage can lead to severe health complications, treatment failures, or harmful drug interactions. Healthcare providers stress the importance of verifying each prescription before taking it.
Every prescription medication has unique identifying characteristics, including specific markings, colors, shapes, and imprint codes like the G037 found on certain pain medications. These features help differentiate similar-looking pills and prevent mix-ups between medications. Pharmacists and doctors rely on these identifiers to double-check prescriptions before dispensing them, while patients can use these markers to verify they received the correct medication.
The FDA requires all prescription medications to carry distinct identifying features, making it easier for everyone involved in healthcare to recognize specific drugs quickly. When receiving a new prescription, patients should confirm the medication matches the doctor’s and pharmacy’s description. Any discrepancies in appearance from previous prescriptions of the same medication warrant immediate discussion with a healthcare provider or pharmacist.
Keeping detailed records of your medications, including photos and descriptions, creates an additional safety measure. This documentation proves especially valuable during emergencies when clear communication about current medications can significantly impact treatment decisions. Many healthcare facilities and pharmacies now provide medication cards or digital records, including images and prescribed medication descriptions.
Prescription medication abuse has emerged as a significant public health challenge, affecting communities across all demographic groups. Medications containing hydrocodone, like the G037 pill, carry a high risk for dependence and misuse due to their effects on the brain’s reward system. People who take these medications for longer than prescribed or in ways other than directed may develop tolerance, requiring increasingly higher doses to achieve the same effects. This pattern often leads to physical dependence and can progress to addiction.
Doctors and pharmacists play a vital role in preventing hydrocodone drug abuse through careful screening, monitoring, and patient education. State prescription monitoring programs help track controlled substance prescriptions, allowing healthcare providers to identify potential misuse patterns early. Physical signs of prescription medication abuse may include drowsiness, confusion, constricted pupils, slowed breathing, and changes in sleep patterns. Anyone experiencing signs of dependence should seek professional help immediately, as attempting to stop these medications suddenly can lead to severe withdrawal symptoms.
Avoid all alcoholic beverages while taking Lortab, as this combination increases the risk of severe liver damage and dangerous central nervous system depression. Grapefruit and grapefruit juice can interfere with how your body processes the medication, potentially leading to higher drug levels in your system. You should also limit other acetaminophen-containing products to prevent exceeding daily limits.
If you miss a dose of Lortab, do not take it if you’re close to your next scheduled dose. Never double up on doses or take extra medication to compensate for the missed dose, as this significantly increases overdose risk. Contact your healthcare professional or pharmacist for guidance if you’re unsure about timing.
Allergic reactions to Lortab require immediate emergency medical attention. Watch for difficulty breathing, wheezing, severe skin rashes or hives, itching, swelling of the face, lips, tongue, or throat, and severe dizziness. Some people may develop blistering or peeling skin reactions. Consider any allergic reaction a medical emergency for you or a loved one, and call 911 immediately.
Taking Lortab during pregnancy requires careful discussion with your healthcare provider. The medication can cause dependency in developing babies, leading to neonatal withdrawal syndrome after birth. Regular use or high doses may also affect fetal development. Healthcare providers weigh the potential benefits against risks, considering factors like pain severity and stage of pregnancy. They often seek alternatives or the lowest effective doses when pain medication is necessary during pregnancy.
[1] Lortab Uses, Dosage & Side Effects. (n.d.). Drugs.com. https://www.drugs.com/lortab.html on January 15, 2025
[2] Cofano, S., & Yellon, R. (2022, October 24). Hydrocodone. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK537288/ on January 15, 2025
[3] Gerriets, V., & Nappe, T. M. (2024, January 11). Acetaminophen. National Library of Medicine; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK482369/ on January 15, 2025
[4] Lortab: Package Insert / Prescribing Information. (n.d.). Drugs.com. https://www.drugs.com/pro/lortab.html on January 15, 2025
[5] Orandi, B. J., McLeod, M. C., MacLennan, P. A., Lee, W. M., Fontana, R. J., Karvellas, C. J., McGuire, B. M., Lewis, C. E., Terrault, N. M., Locke, J. E., & US Acute Liver Failure Study Group. (2023). Association of FDA Mandate Limiting Acetaminophen (Paracetamol) in Prescription Combination Opioid Products and Subsequent Hospitalizations and Acute Liver Failure. JAMA, 329(9), 735–744. https://pmc.ncbi.nlm.nih.gov/articles/PMC9993184/ on January 15, 2025
[6] Mayo Clinic. (2024). Hydrocodone And Acetaminophen (Oral Route) Description and Brand Names – Mayo Clinic. Www.mayoclinic.org. https://www.mayoclinic.org/drugs-supplements/hydrocodone-and-acetaminophen-oral-route/description/drg-20074089 on January 15, 2025
[7] Mayo Clinic. (2024). Hydrocodone And Acetaminophen (Oral Route) Description and Brand Names – Mayo Clinic. Www.mayoclinic.org. https://www.mayoclinic.org/drugs-supplements/hydrocodone-and-acetaminophen-oral-route/description/drg-20074089 on January 15, 2025
[8] Cofano, S., & Yellon, R. (2022, October 24). Hydrocodone. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK537288/ on January 15, 2025
[9] National Library of Medicine. (2016, January 28). Acetaminophen. Nih.gov; National Institute of Diabetes and Digestive and Kidney Diseases. https://www.ncbi.nlm.nih.gov/books/NBK548162/ on January 15, 2025