Toradol and tramadol are both used to treat pain, but they work in very different ways and carry different risks. People often compare them because they may be offered for similar pain situations, such as after surgery or injury, yet they are not interchangeable. Understanding how each medication works can help clarify why a clinician might choose one over the other.
What Is Toradol (Ketorolac)?
Toradol is the brand name for ketorolac, a nonsteroidal anti-inflammatory drug (NSAID). It treats pain by reducing inflammation through inhibition of prostaglandins, the chemicals involved in pain and swelling.
Toradol is commonly used for short-term, moderate to severe acute pain, often in hospital or emergency settings. It is frequently given by injection or IV, though oral forms exist. Because of safety concerns, Toradol is typically limited to no more than five days of use.
Toradol (Ketorolac) Pill Identifiers
Toradol is the brand name for ketorolac. Oral ketorolac tablets are typically used short term and have more consistent appearance than tramadol.
Table 1. Common Toradol (Ketorolac) Tablet Identifiers
| Dosage | Form | Common Color / Shape | Typical Markings |
|---|---|---|---|
| 10 mg | Oral tablet | White or off-white; round | “93 314,” “KET 10,” “10” |
| 10 mg | Oral tablet (generic) | White; round | Manufacturer-specific numeric codes |
Important note: Ketorolac tablets are usually limited to short-term use and are often prescribed after injectable dosing. Longer use increases the risk of stomach, kidney, and bleeding complications.
What Is Tramadol?
Tramadol is a centrally acting opioid-like pain medication. It works by binding to opioid receptors and also affecting serotonin and norepinephrine levels in the brain. This dual action can help reduce the perception of pain.
Tramadol may be prescribed for moderate pain, sometimes when other pain relievers are not effective or appropriate. Unlike Toradol, tramadol can be prescribed for longer periods, though that increases certain risks.
Tramadol Pill Identifiers
Tramadol tablets come in multiple strengths and may look different depending on the manufacturer. Always verify medications using the prescription label or an official pill identifier.
Table 2. Common Tramadol Tablet Identifiers
| Dosage | Form | Common Color / Shape | Typical Markings |
|---|---|---|---|
| 50 mg | Immediate-release tablet | White, off-white, or light yellow; round or capsule-shaped | “UL 50,” “AN 627,” “377,” “H 7” |
| 100 mg | Extended-release tablet | White or light-colored; capsule-shaped | “ER 100,” manufacturer-specific codes |
| 200 mg | Extended-release tablet | White; capsule-shaped | “ER 200,” manufacturer-specific codes |
| 300 mg | Extended-release tablet | White; capsule-shaped | “ER 300,” manufacturer-specific codes |
Important note: Extended-release tramadol tablets should not be crushed or split. Street versions or diverted pills may not match legitimate identifiers and can be counterfeit.
How Toradol and Tramadol Work Differently
The biggest difference between Toradol and tramadol is how they relieve pain. Toradol targets inflammation at the source, which makes it especially useful for pain caused by swelling or tissue injury. Tramadol changes how the brain processes pain signals, which can help even when inflammation is not the primary issue.
Because of this, Toradol does not cause opioid effects such as euphoria, while tramadol can, particularly at higher doses or with prolonged use.
Table 3. Toradol vs. Tramadol: Key Differences
| Feature | Toradol (Ketorolac) | Tramadol |
|---|---|---|
| Drug class | NSAID | Opioid-like analgesic |
| Treats inflammation | Yes | No |
| Risk of dependence | No | Yes |
| Common setting | ER, hospital, short-term outpatient | Outpatient or short-term inpatient |
| Duration limits | Max 5 days | Can be longer with monitoring |
| Sedation effects | Minimal | Possible |
| Controlled substance | No | Yes (Schedule IV) |
Pain Relief Strength Comparison of Toradol vs. Tramadol
Toradol is often described as providing strong pain relief similar to opioids for certain types of acute pain, especially post-surgical pain, without the addictive risk. However, it is not appropriate for chronic pain.
Tramadol may be less effective for inflammation-based pain but can help with nerve-related or centralized pain. Because it affects opioid receptors, it may feel stronger to some people, but this also increases risk.
Side Effects and Risks of Toradol vs. Tramadol
Toradol’s risks involve the stomach kidneys, and bleeding, especially with longer use or in older adults. It can increase the risk of ulcers or kidney injury if used improperly.
Tramadol’s risks include dependence, withdrawal, dizziness, sedation, and serotonin syndrome, particularly when combined with antidepressants or other serotonergic medications. Seizure risk can also increase at higher doses.
Which Is Safer Between Toradol vs. Tramadol?
Neither medication is universally safer. Safety depends on:
- Type and cause of pain
- Length of treatment
- Medical history
- Other medications being taken
For short-term inflammatory pain, Toradol is often preferred due to its non-opioid profile. For pain not driven by inflammation, tramadol may be considered, but with careful monitoring.
Why Tramadol Raises More Long-Term Concerns than Toradol
Unlike Toradol, tramadol can lead to physical dependence, even when taken as prescribed. Stopping tramadol abruptly after regular use can cause withdrawal symptoms, including anxiety, flu-like symptoms, and sleep disruption.
Because tramadol also affects serotonin, it carries added risks when combined with certain antidepressants or stimulants.
The Bottom Line
When comparing Toradol vs tramadol, the choice comes down to the type of pain being treated and the risks involved. Toradol is a short-term, non-opioid option well-suited for acute inflammatory pain. Tramadol works differently and may help certain pain conditions but carries higher risks, particularly with longer use.
If pain persists or medication use becomes ongoing, it’s important to reassess treatment options rather than continuing either medication without follow-up.
Support for Tramadol Dependence and Withdrawal
While tramadol is often prescribed for pain, it can be difficult to stop after regular use. Because tramadol affects opioid receptors and serotonin levels, some people experience withdrawal symptoms or mood changes when trying to taper or discontinue it.
If tramadol use has become hard to manage, structured treatment can help support a safer transition off the medication and address the underlying reasons it was prescribed or continued. Brooks Healing Center services include:
- Medical Detox
- Medication-Assisted Treatment (MAT)
- Residential Treatment
- Partial Hospitalization Program (PHP)
Seeking support does not mean failure. For many people, it’s a practical step toward stabilizing pain management, mental health, and overall well-being.
Frequently Asked Questions about Tramadol vs Toradol
Is Mavidol the same as tramadol?
No. Mavidol and tramadol are not the same medication. Mavidol is an over-the-counter pain reliever that typically contains acetaminophen or similar non-opioid ingredients, while tramadol is a prescription pain medication that acts on opioid receptors and affects brain chemistry.
Is Toradol addictive?
Toradol is not considered addictive in the way opioids are. It does not produce euphoria or cravings, but misuse or extended use can still cause serious health problems, particularly related to the stomach, kidneys, and bleeding risk.
Is Toradol a controlled substance?
No. Toradol is not a controlled substance. It is classified as a nonsteroidal anti-inflammatory drug (NSAID) and does not carry scheduling under the Controlled Substances Act.
Is tramadol a controlled substance?
Yes. Tramadol is a Schedule IV controlled substance in the United States due to its potential for misuse, dependence, and withdrawal, even when taken as prescribed.
Can you take Toradol and tramadol together?
In some medical settings, Toradol and tramadol may be prescribed together for short-term pain management, but this should only be done under medical supervision. Combining medications always increases the risk of side effects and should not be done without guidance from a healthcare provider.
Does Toradol come in pill form?
Yes. Toradol is available in pill form, though it is more commonly given by injection or IV in hospitals. Oral Toradol is typically prescribed for very short-term use due to safety concerns.
Is tramadol an anti-inflammatory drug?
No. Tramadol is not an anti-inflammatory medication. It works by altering how the brain perceives pain and does not reduce inflammation like NSAIDs such as Toradol or ibuprofen.
Are tramadol and Toradol the same?
No. Tramadol is not a blood thinner. However, it can still increase bleeding risk when combined with certain medications, which is why drug interactions should always be reviewed by a healthcare provider.
Sources
- MedlinePlus. (n.d.). Ketorolac. U.S. National Library of Medicine. Retrieved from MedlinePlus.gov
- MedlinePlus. (n.d.). Tramadol. U.S. National Library of Medicine. Retrieved from MedlinePlus.gov
- Drug Enforcement Administration. (2014). Schedules of Controlled Substances: Placement of Tramadol Into Schedule IV. Federal Register, 79(127), 37623–37630. Retrieved from GovInfo.gov
- Drug Enforcement Administration. (n.d.). Controlled substance schedules. Retrieved from DEA.gov
- DailyMed. (n.d.). Tramadol hydrochloride prescribing information. Retrieved from DailyMed (FDA)
- National Institute on Drug Abuse. (n.d.). Prescription opioids. Retrieved from NIDA.nih.gov
